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 Sonali Bose Ph.D. candidate Research interests: • Enhancement of transdermal/topical delivery of poorly water-soluble molecules, comparison of various routes of delivery (buccal vs transdermal). Current research: • Development and characterization of a topical/transdermal delivery system for the dietary flavonoid quercetin. Experience: • M.S. in Pharmaceutical Sciences from Duquesne University, Pittsburgh • B.S. in Pharmaceutical Sciences from Jadavpur University, India • Senior Scientist at Novartis Pharmaceuticals based in East Hanover, New Jersey • Experience in solid dosage formulation development starting from pre-formulation (Phase I) all the way to scale-up and handover of process to technical operations for commercialization  Indrajit GhoshResearch Scientist – Novartis Pharmaceutical Corporation Research Interests: Preformulation development and characterization, formulation development of Solid dispersion using Melt Extrusion technology, drug delivery technology using Transdermal drug delivery system. Experience: • Research Scientist, Pharmaceutical Development of Oncology and Antihypertensive group of drugs using Solid Dispersion technology and characterization of different polymorphic forms of Drug molecules, Novartis Pharmaceutical Corporation, East Hanover, NJ, USA (Feb 2005 –Present) • Formulation Development Scientist, Formulation Development on Solid Dosage Forms using Multilayer compression technology, Ranbaxy Pharmaceutical Inc., New Brunswick, NJ, USA (2002 –2005) • Research Executive, Formulation and Process development on Biopharmaceutical Class II and Class IV category Oral solid dosage forms, Zydus Cadila Healthcare, India (2001-2002) • Research and Development Officer- Drug pre-formulation and formulation studies on Soft Gelatin Capsule formulation of poorly soluble compounds, Dr. Reddy’s Laboratories, India (1999-2001) • MS in Pharmaceutical Science with thesis submitted on Transdermal Drug Delivery System, Jadavpur University, India (1997-1999) • BS in Pharmaceutical Science, Jadavpur University, India (1993-1997) Selected Publications: • "Statistical Optimization of Transdermal Drug Delivery System of Terbutaline Sulphate" in Journal of Bollettino Chemico Farmaceutico, January - February, 2000. No. 1, page 26. • “Design and evaluation of an oral controlled release microparticulate drug delivery system of a NSAID by Ionotropic Gelation Technique and Statistical optimization by factorial analysis” in Journal of Scientific Industrial Research, Volume 58, September, 1999, p 717-722. Patents: • Drug Delivery of 2 incompatible molecules by Multilayer compression technology, (Filed). • Improving Bioavailability a poor soluble compound, (Filed). • Solid Dispersion technology, (Filed). Back to top  Golshid KeyvanResearch Assistant Education: • B.S. in Chemical Engineering, Columbia University • M.S. in Chemical Engineering, Columbia University Experience: • Research Assistant, Bristol-Myers Squibb • Research Assistant, Engineering Resource Center, Rutgers University Back to top .jpg) Brian E. Kilfoyle Ph.D. candidate Research interests: • Use of polymeric nanospheres as delivery vehicles into / across biological membranes. • Permeation analysis across skin, buccal tissue, and synthetic membranes. Current research: • Optimization of nanosphere-drug formulations • in vitro transmucosal permeation studies • Development of a synthetic membrane for transdermal testing • Use of polymer systems to prevent transdermal penetration • Drug permeation studies of different drugs and formulations across different biological membranes e.g. skin, buccal membranes, polymeric membranes. Experience: • New Jersey Center for Biomaterials, Piscataway, NJ Research Assistant (June 2008-Present) • Ernest Mario School of Pharmacy, Teaching Assistant (2007-2008) • Scientist I - characterization dry powders for pulmonary drug delivery at Microdose Technologies – Monmouth Junction, NJ (2006-2007) • Scientist I - responsibilities in spray drying and characterizion of powders for pulmonary drug delivery and formulation development for sustained release injectables – Alkermes, Inc. – Cambridge, MA (2005-2006) • Research Associate II – Designed and evaluated drug delivery systems for topical, transdermal, and transungual delivery - MacroChem Corp – Lexington, MA (2001-2005) Selected Publication and patents: • Diksha Kaushik,Priya Batheja, Brian Kilfolye, Vishwas Rai and Bozena Michniak-Kohn. Percutaneous permeation modifiers: enhancement and retardation. Expert Opinion, Drug Delivery 2008; 5(5):517-529 Back to top  Vishwas RaiPh.D. candidate Research interests: • Development and analysis of Human Skin Equivalents (HSE). • Permeation analysis across biological and polymeric membranes. Current research: • Cell culture and bioengineering of HSE. • Histological, Lipid and Gene Expression analysis of human/animal skin, HSE and other membranes. • Creation of polymeric scaffold for improving mechanical strength of HSE. • Mechanical testing of the scaffolds & HSE. • Drug permeation studies of different drugs and formulations across different biological membranes e.g. skin, buccal, polymeric and HSE. Experience: • New Jersey Center for Biomaterials, Piscataway, NJ Research Assistant (June 2007-Present) • Ernest Mario School of Pharmacy, Teaching Assistant (2008-Present) • Summer Intern, Varian Inc., Walnut Creek, CA (2006) • University of the Pacific, Teaching Assistant (2004-2007) • Mass Spectroscopic Analysis for Flavor House Inc, Adelanto, CA (2005) • Production Supervisor in manufacturing of Tablets, Capsules and Dry-syrups, Delta Aromatics, Okla, New Delhi, India (2003) Selected Publication and patents: • Vishwas Rai, Jenna Terebetski and B.Michniak-Kohn, Human Skin Equivalents as Alternatives for Transdermal Permeation, Phototoxicity and Cytotoxicity Studies, Transdermal, May 2010, Volume 2, Number 3, 5-8 • Vishwas Rai, Indrajit Ghosh, Sonali Bose, Sergio M. C. Silva, Prafulla Chandra, Bozena Michniak-Kohn. A transdermal review on permeation of drug formulation, modifier compounds and delivery methods. Journal of Drug Delivery Science and Technology (JDDST), France, 2010, 20 (2): 75-87 • Diksha Kaushik, Agis Kydonieus, Vishwas Rai and Bozena Michniak-Kohn, Pharmaceutical Science and Technology-Patent Watch, Control Release Society Newsletters 2009; Volume 29 No. 1: 32-41 • Diksha Kaushik,Priya Batheja, Brian Kilfolye, Vishwas Rai and Bozena Michniak-Kohn. Percutaneous permeation modifiers: enhancement and retardation. Expert Opinion, Drug Delivery 2008; 5(5):517-529 • Priya Batheja, Vishwas Rai, Prafulla Chandra and Bozena Michniak An In Vitro Skin Equivalent for Evaluation of Skin Absorption of Compounds (KP-07) 26th Army Science Conference, sponsored by the Assistant Secretary of the Army, Orlando, Florida, December 1-4, 2008. Conference theme: "Transformational Army Science and Technology - Harnessing Disruptive S&T for the Soldier." Back to top  Sérgio Silva Ph.D. candidate Research interests: • Permeation studies and transdermal drug delivery (using chemical enhancers and iontophoresis). • Formulation development. • Polymers and surfactants – thermal gelation, interaction mechanisms and rheological studies. Current research: • In-vitro permeation studies and analysis. • Use of hydrogels as drug delivery vehicles for permeation across the skin. • Transdermal drug delivery using skin penetration enhancement techniques (chemical enhancers and iontophoresis). • Cell culture and citotoxicity studies. Experience: • 2007- : Ph.D. candidate, Faculdade de Farmácia, Universidade de Coimbra, Portugal /visiting student at New Jersey Center for Biomaterials / Ernest Mario School of Pharmacy, Rutgers University, NJ, USA. • 2005- 2006: Quality Assurance manager at Labialfarma – Portugal • 1999- 2005: Faculdade de Farmácia, Universidade de Coimbra. Undergraduate student. Selected Publication and patents: • Vishwas Rai, Indrajit Ghosh, Sonali Bose, Sergio M. C. Silva, Prafulla Chandra, Bozena Michniak-Kohn. A transdermal review on permeation of drug formulation, modifier compounds and delivery methods. Journal of Drug Delivery Science and Technology (JDDST), France, 2010, 20 (2): 75-87 • Sérgio M.C. Silva, Fátima V. Pinto, Filipe E. Antunes, Maria G. Miguel, João J.S. Sousa, Alberto A.C.C. Pais. Aggregation and gelation in hydroxypropylmethyl cellulose aqueous solutions. Journal of Colloid and Interface Science 327 (2008) 333–340. Back to top  Jenna TerebetskiPh.D. candidate Research interests: • Drug delivery technologies for poorly water-soluble molecules, preformulation studies,pharmacokinetics/ADME, and specialized delivery systems for proof of concept pharmacology studies. Current research: • Use of polymer systems for oral drug delivery Experience: • Research Chemist - Preformulation to support selection of leads in discovery and clinical candidates in development; phase and formulation identification for pharmacology and toxicology studies - Merck Research Laboratories, Rahway, NJ, USA (June 2004 -Present) Back to top  J. Peter Zhang Senior Scientist - Schering Plough Corporation Research interests: Drug delivery technology, pre-formulation studies, formulation development, pharmacokinetics/ADME, polymeric drug delivery systems, and pathological mechanism studies. Current research: Transdermal drug delivery, permeation enhancers and their mechanisms, novel drug delivery techniques, and topical and transdermal formulation studies. Experience: • Drugs and their metabolites analyses and characterizations / Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, China. • Drug pre-formulation and formulation studies, pharmaceutical analyses, laboratory automation and electronic documentation; / Schering-Plough Corporation, New Jersey. Selected Publications and patents: • J. Zhang, B.A. Watson, R.W. Keown, C.P. Malone and M.A. Barteau "Investigation of sulfonated aromatic compound (SAC) modification to nylon 6 film. 2. Study of SAC sorption isotherm and atomic force microscopic characterization of nylon surface" Langmuire 11(8):3018-3023, 1995 • J. Zhang, C.S. Liu and T.H. Zhou "The analysis of human urinary metabolites of the contraceptive drug norethisterone by GC-MS". Chemical J. Chinese Universities 14(2):184-186, 1993 • J. Zhang, C.S. Liu, H. Bi, Y. Zhang, L. Ye and T.H. Zhou "The Chromatographic-Mass Spectrometric Analysis and Detection of Anabolic Steroid drugs in Human Urine and Metabolic Study" Acta Pharmaceutica Sinica 26(8):598-605, 1991 Back to top  Zheng ZhangResearch Associate Research interests: • Biodegradable polymer matrices and networks for controlled drug delivery and tissue engineering applications; • Angiogenesis Current research: • To prepare and characterize the tyrosine-derived, drug-loaded nanospheres and to investigate the effect of drug-loaded nanospheres on in vitro cellular bioresponse. • To investigate the percutaneous penetration and skin distribution of the drug-loaded nanospheres in vitro. • In vivo evaluation of drug-loaded nanospheres in preclinical psoriasis studies. Experience: • 1994-1999: Department of Polymer Science and Engineering, University of Science and Technology of China (USTC), Hefei, China. Undergraduate; • 1999- 2001: Department of Polymer Technology, Åbo Akademi University, Turku, Finland. Master; • 2001-2005: Department of Polymer Chemistry and Biomaterials (PBM), University of Twente, the Netherlands. PhD; • 2005- 2007: PostDoc researcher at the same group; • 2007-2009: University Docent at the same group; • June 2008-Sep. 2008: Visiting scientist in Professor Teruo Okano’s group at Institute of Advanced Biomedical Engineering and Science, Tokyo Women’s Medical University; • 2010-: New Jersey Center for Biomaterials. Research Associate. Selected Publication and patents: • Z. Zhang, D.W. Grijpma, J. Feijen; “Triblock copolymers based on 1,3-trimethylene carbonate and lactide as biodegradable thermoplastic elastomers”, Macromolecular Chemistry and Physics 205: 867-875, 2004. • Z. Zhang, R. Kuijer, S.K. Bulstra, D.W. Grijpma, J. Feijen; “The in vivo and in vitro degradation behavior of poly(trimethylene carbonate)”, Biomaterials 27:1741-1748, 2006. • Z. Zhang, D.W. Grijpma, J. Feijen; “Poly(trimethylene carbonate) and monomethoxy poly(ethylene glycol)-block-poly(trimethylene carbonate) nanoparticles for the controlled release of dexamethasone”, Journal of Controlled Release 111: 263-270, 2006. Back to top  James WintersUndergraduate Research Interests: • Tissue regeneration and pharmaceutical design and Synthesis Current Research: • Topical drug delivery using tyrosine-derived nanoparticles to treat Psoriasis Experience: • NJ Center for Biomaterials - Laboratory Technician Back to top  David WintersUndergraduate Research Interests: • Tissue engineering, enhancement of topical drug delivery methods Current Research: • Topical drug delivery utilizing tyrosine-derived nanoparticles to treat Psoriasis Experience: • NJ Center for Biomaterials - Laboratory Technician Back to top |
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