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External investigators are encouraged to inquire about how they can collaborate with RESBIO. Eligible projects should have:
- Potential to challenge one or more of the core technologies technically
- Potential to make a core technology relevant to more areas of biomedical research
- Potential to extend the underlying science of the technology
- Expectation of significance and productivity after one year
- Independent funding.
Selected projects will receive collaborative resources from RESBIO but no direct financial support.
RESBIO was approached by the NIBIB P41Center for Neural Communication Technology (CNCT) at the University of Michigan and Wadsworth Center to address a technical challenge in the placement of probes into brain tissue for the purpose of stimulating and reading neural signals. Core S of RESBIO is designing and synthesizing absorbable polymers to overcome deficiencies of the non-absorbable polymers currently being used. To learn more about CNCT click here. Doyle Knight of Rutgers, Robert Latour of Clemson (Core C Leaders), Larisa Sheihet of Rutgers and Aurora Costache of Rutgers have initiated studies on development and application of computational tools to understand the polymer-drug interactions in drug delivery systems and to predict the drug release for polymeric devices. Dr Julia Babensee and her team at GA Tech are studying the effect of polymeric biomaterials on activation of dendritic cells (DC). After developing a high-throughput assay for testing DC activation, they approached RESBIO to recommend polymer libraries that could be tested. RESBIO not only is providing polymer libraries for this collaborative project but is also developing a high-throughput testbed with selected polymer coatings that can be seamlessly fitted into the GA Tech testing method to enable rapid screening of polymeric biomaterials.
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