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Home: RESBIO: Training Opportunities: Cells on Polymeric Biomaterials

Cells on Polymeric Biomaterials – A short course
offered by RESBIO, Technology Resource for
Polymeric Biomaterials




Profs. Prabhas Moghe (left) and Pallassana Narayanan (front) with attendees of the  Cells on Polymeric Biomaterials short course, October 29, 2009. 


2010 Short Course dates will be announced by March

The Course Overview
Cells on Polymeric Biomaterials is an in-depth 3-day short course designed for scientists and engineers to gain an understanding of how cells and proteins interact with materials.  Scientific personnel and managers of interdisciplinary teams involved in tissue engineering or regenerative medicine, and anyone whose research touches on cell-material interactions, can benefit from instruction in novel approaches to accelerate the pace of discovery.  The anticipated outcomes are better design of new medical implants and improved performance of existing devices. Significant emphasis will be placed on hands-on training so that participants can evaluate the available RESBIO resources and continue to use these resources for their needs even after the course.

Three major topics on materials, confocal microscopy and computational modeling will be covered with one day allocated for each topic.  The format of each day will be morning lectures and afternoon hands-on training.  The materials topic will cover synthesis, fabrication and characterization of polymeric biomaterials. Perspectives on synthesis, processing and characterization in the context of product and process development, validation and regulatory submission will be presented.  The confocal microscopy section will focus on cells-material sample preparation, imaging and analysis. The computational modeling course introduces the public interested in modeling of polymeric biomaterials to the state-of-he art molecular modeling tool Biomaterials StoreTM, developed at Rutgers Center for Computational Design and New Jersey Center for Biomaterials. The workshop will provide an introduction to the tools available in Biomaterials StoreTM and also a hands-on session where the users will work through a tutorial on the software. Click here for more details.

Course Outline

Day 1 Polymer Synthesis, Substrate Fabrication and Material Characterization, 9 AM - 5 PM
Morning: Combinatorial Computational Approach
    Design of Polymer Libraries
    Parallel Synthesis of Polymer Libraries

Fabrication of Implants/Scaffolds for Studying Cell Behavior and Water Uptake
    Filament/Fiber Extrusion
    Electrospinning
    Casting and coatings
    Compression and Injection Molding

Material Characterization for Structure-property-behavior Correlations
    QCMD – Protein adsorption on biomaterials
    DSC, TGA – Degradation and water uptake
    Mechanical – Load bearing and deformation
    HPLC / GPC – Molecular weight
    NMR – Composition for validation of synthesis step
    Microscopy (Optical, SEM, TEM) – Surface
characterization
    PCR – Gene expression and regulation, receptor
up/down regulation
Afternoon: Hands-on training and demonstrations of synthesis, fabrication and characterization of polymeric biomaterials and scaffolds

Day 2 Imaging of the Interactions of Cells on Biomaterials, 9 AM - 5 PM
Morning: Overview of Confocal / Multiphoton Microscopy
    Theory and applications: Confocal/multiphoton
white light/epi-fluorescent
    Equipment: Leica Imaging Suite
    Operation: Basic protocols
    Sample Preparation: 2D substrate, scaffold
preparation
    Imaging and Interpretation
    Equipment tour
Morning & Afternoon: Hands-on Training on Sample Preparation and Imaging
   3D imaging-based scaffold microsctructure
characterization
   Multimodal imaging of cells on 2D films & 3D
scaffolds
    Cell seeding and imaging on 3D biomaterials
    High-throughput imaging of cells on 3D
scaffolds.
   Setup of time lapse studies to track tagged /
fluorescently engineered cells
   Viral engineering of primary cells

Day 3 Semi-empirical Modeling of Bioresponse using Biomaterials StoreTM, 9 AM - 5 PM
Morning: Overview
            Theory of semi-empirical modeling
            Biomaterials StoreTM Part I: MySQL
            Biomaterials StoreTM Part II: WEKA
Afternoon: Computer Lab – Modeling hands-on training

Registration:

Industrial Participants:
$600 for the entire course
$200, daily rate

Academic Participants:
$400 for the entire course
$150, daily rate

Those participants, who do not wish to attend all three days but choose to attend selected topics only, can register at the daily rate indicated above.

Cancellation Policy: The full amount paid minus a $50 processing fee will be refunded for cancellations received prior to October 14, 2009.  No refund will be issued for cancellations received after October 14, 2009.  Late requests for refunds due to an emergency only will be considered on a case-by-case basis.

All cancellations and requests for refunds MUST be submitted in writing
via e-mail, fax, or mail by October 14, 2009. Telephone requests will not be honored.

Short Course Location


NJ Center for Biomaterials
145 Bevier Road
Piscataway, NJ 08854

Accommodation

Rutgers Inn
178 Ryders Lane
New Brunswick, NJ 08901-8556
Phone: (732) 932-9144
Fax: (732) 932-6952
http://univinn.rutgers.edu

Heldrich, New Brunswick
10 Livingston Avenue
New Brunswick, NJ 08901
Phone: (866) 609-4700
http://www.theheldrich.com

Hyatt, New Brunswick
2 Albany Street
New Brunswick, NJ 08901
Phone: (732) 873-1234
http://www.newbrunswick.hyatt.com

Questions, Contact


Pallassana Narayanan PhD
NJ Center for Biomaterials, Rutgers University,
Chief Operating Officer, RESBIO
145 Bevier Road
Piscataway, NJ 08854

Phone: 732-445-0488 ext 40021
Fax: 732-445-5006
Email: pnarayan@biology@rutgers.edu

Website Link

http://www.njbiomaterials.org/web/index.php?p=resbio