Videos 2012

  • 4/2/2012 Obviousness and Formulation Patents - Michael Davitz  M.D, J.D Axinn, Veltrop and Harkrider LLP 

    BioMichael A. Davitz is a partner at Axinn, Veltrop & Harkrider LLP in the firm’s Intellectual Property and Biomedical Practice Groups, where his practice focuses on intellectual property rights. He is a registered U.S. patent attorney as well as a physician with more than 15 years of experience in biomedical research, and has provided strategic counseling for more than a decade to clients in all aspects of intellectual property law. 
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  • 4/23/2012 Facile Production of Nanoparticles for Dificult to Deliver Therapeutics - Robert Prudhomme Ph.d 

    Bio: Dr. Prud'homme received his BS at Stanford University and his PhD from the University of Wisconsin at Madison under Professor Bob Bird. His research interests include rheology and self-assembly of complex fluids. Systems of interest are biopolymer solutions and gels, surfactant mesophases and polymer/surfactant mixtures. His studies seek to understand how weak molecular-level interactions can be used to tune macroscopic bulk properties and phase behavior. Application of the work is directed at nanoparticle formation for drug delivery, controlled release, targeting and imaging.
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  • 6/11/2012 Deperately Seeking Synergy - Joseph Albanese Ph.d - 3V Inc.

    AbstractVery simply, Desperately Seeking Synergy is an introduction to the benefits derived from the proper utilization of Experimental Design. It provides a strategy for setting up experiments that are most appropriate for optimizing formulations. These are called Mixture Designs. It covers several DOE (Design of Experiments) software programs and provides several approaches for determining whether or not you formula has hit that "sweet spot" where the interactions of key ingredients produce a winning synergistic combination 
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  • 8/272012 Suncare and Skin New Dermatological Strategies - Robert Falcone  Ph.d  Peter Thomas Roth Labs

    Abstract: At the present moment sunscreens are considered the best sun care technology for sun care protection. This presentation will review the present and proposed technologies that can be used in short and long term skin protection and maintenance.
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  • 9/11/2012 Roles Of Lipids In The Barrier Functions Of Skin And Oral Mucosa - Philip Wertz Ph.d Dows Institute at the University of Iowa

    Abstract: Epidermal stratum corneum contains mainly ceramides, cholesterol, fatty acids and small amounts of cholesterol sulfate.  Precursors to these  lipids are delivered to the intracellular space via lamellar granules.  A battery of hydrolytic enzymes convert the precursors into the mature stratum corneum lipids.  The lipids in epidermal stratum corneum are organized into 13-nm trilaminar structures as revealed by transmission electron microscopy using ruthenium tetroxide as a fixative. An unusual linoleate containing acylceramide appears to be required for this lamellar organization. In-keratinized oral epithelium from the hard palate and gingival, lipids are delivered to the intercellular spaces via lamellar granules.  The lamellae in the intercellular spaces of oral stratum corneum do not appear as organized as those in epidermal stratum corneum, and the trilamellar units are not apparent.  The lipid class composition of oral stratum corneum is similar to that of epidermal stratum corneum, except that small proportions of phospholipids and glucosylceramides persist.  In the nonkeratinized regions of oral epithelium (floor of mouth and buccal regions) there are two types of secretory organelles of about the same size as lamellar granules that deliver things to the intercellular space:  cored granules and lamellate granules.  It appears that the lamellate granules deliver lipids to the intercellular space.  Short stacks of lamellae are arranged transversely across the intercellular spaces in these regions at irregular intervals.  In all regions of skin and oral mucosa, sphingosine and dihydriosphingosine derived from sphingolipids provide antimicrobial activity.  Also, at the skin surface and in the oral cavity, lauric acid and sapienic acid (C16:1Δ6) derived from sebaceous triglycerides are also antimicrobial.  These antimicrobial lipids have implications for cutaneous and oral health and disease.
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  • 9/24/2012 Update on US Sunscreen Regulations - David Steinberg MBA  Steinberg and Associates

    Abstract: This presentation will review the uses of sunscreens and the radiation which sunscreens are focusing on. The history of regulations of sunscreens will be covered including the increasing of permitted  SPF and the cancer warning claims though the years. The major emphasis will be on the latest and current regulations. This review will cover the proper and required labeling of the product with a “how to” create a Drug Facts panel.  Also covered will be the options if it doesn’t fit the space you have available on your packaging. The tests which you must run will be addressed along with prohibited claims.  There will be a review of “unfinished” FDA rulemaking and how this will affect the future in the marketplace. Complete registrations of drugs will be presented and included will   be who is responsible to file what. Finally the FDA’s issues with “unapproved” types of sunscreens will be covered along with industry’s responses on this complex area 
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